Duke Leto Atreides is now the skilful and much-loved ruler of Caladan, served by loyal Duncan Idaho. To his court come Gurney Halleck, despised slave of the Harkonnens - and Jessica, the exquisite, perfectly trained concubine chosen by the Reverend Mothers of the Bene Gesserit to be the mother of Leto's daughter. Meanwhile, on Dune - planet Arrakis - House Harkonnen ruthlessly harvests the precious, mind-enhancing drug called spice.

And Baron Vladimir is slowly being consumed by a loathesome disease. Rabban Harkonnen - House Atreides' most implacable enemy - prepares to take over his uncle's empire.