Elizabeth Darcy is the happiest woman alive when she steps into the carriage that is to take her on her wedding tour - until she sees the look of torment on Mr Darcy's face and discovers that he has a deep, dark secret that nearly destroys their love, their marriage and even her very life. Darcy and the rest of his family are vampires that cannot be outside during sunrise or sunset. Lady Catherine is at the source, having turned Georgiana into an undying friend for her vampiric daughter, Anne, and then Darcy as the perfect mate for Anne.

Now Lizzy and Darcy must travel across the Continent to the Pyrenees to find a way to break the curse. But Lady Catherine won't give up her undead without a fight - The Y in "Vampyre" is a tribute to the first vampyre story in print in the English language called simply "The Vampyre". It was written by John Polidori, a physician in the employ of Lord Byron and who, whilst staying by Lake Geneva with Mary Wollstonecraft Godwin, Percy Bysshe Shelley and Mary's stepsister Claire Clairmont amused themselves by reading and writing ghost stories.

Two of the greatest horror stories came from that night Mary Shelly's "Frankenstein" and "The Vampyre".